astrazeneca vaccine ingredients pdf
endstream endobj 780 0 obj <. 4 to 12 weeks. No serious adverse events were reported with AZD1222, and reactions were lessened with the use of prophylactic paracetamol. Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take, any other medicines or vaccines. You will be told when you need to return for your second injection of COVID-19 Vaccine AstraZeneca. 56 0 obj A very rare adverse event called Thrombosis with Thrombocytopenia Syndrome (TTS), involving unusual and severe blood clotting events associated with low platelet counts, has been reported after vaccination with this vaccine. As new data become available, WHO will update recommendations accordingly. RZ%L ?Gss0~ls"+?H~9~ ~~g5-?K~=2_H 0000098136 00000 n Do not use COVID-19 Vaccine AstraZeneca after the expiry date which is stated on the label after EXP. Keep vials in outer carton to protect from light. %%EOF %PDF-1.6 % impact. 0000003223 00000 n This phase also helps researchers understand how well a vaccine works over a longer time frame and how safe it is for the population. If you experience any of the following from around 4 days after vaccination you should seek medical advice urgently: Tell your doctor, pharmacist or nurse if you experienced a blood clot occurring at the same time as low levels of platelets after receiving a previous dose of the vaccine. 0000102371 00000 n ____________________________________________________________________________________. The vaccine does not contain any preservative and should be administered by a healthcare professional. up to 16 weeks can be considered. Well send you a link to a feedback form. But individuals may choose to delay vaccination for 3 months following the infection. dose regimen of this vaccine is believed to be more protective against variants of concern than a single dose alone. Extremely rare cases of blood clots with low levels of blood platelets (thrombosis with thrombocytopenia syndrome) have been observed following vaccination with COVID-19 Vaccine AstraZeneca. 0000024847 00000 n If you get any side effects, talk to your doctor, pharmacist or nurse. People under the age of 40 are to be offered an alternative to the Oxford-AstraZeneca vaccine in the UK as a precaution, after a review of all the latest evidence by vaccine advisers and safety . Something went wrong while submitting the form. You cannot usually choose which vaccine you have. %PDF-1.7 % WHO recommends focusing on achieving high first dose coverage by extending the inter-dose interval, whilst continuing to maximize second dose coverage of vulnerable groups in the context of variants of concern. To view this licence, visit nationalarchives.gov.uk/doc/open-government-licence/version/3 or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: psi@nationalarchives.gov.uk. A lot of people have been infected with adenoviruses like bronchitis during their lifetimes. Your doctor, pharmacist or nurse is responsible for storing this vaccine and disposing of any unused product correctly. It is your choice to receive the COVISHIELD . 0000104331 00000 n AstraZeneca is a member of Covax, a global initiative aiming to distribute two billion vaccine doses to 92 low- and middle-income countries at no more than $3 a dose. Vaxzevria is made up of another virus (of the adenovirus family) that has been modified to contain the gene for making a protein from SARS-CoV-2, the virus that causes COVID-19. i; "32tBa;CC'd&@u^?^02/g`8Ea?U k [ O'`` r/ RV"Lj~=n%8w?C * The AstraZeneca vaccine uses a harmless, weakened animal virus (called a viral vector) that contains the genetic code for the coronavirus spike protein. 0000001596 00000 n Each vial contains 10 doses of 0.5 ml. syndrome [GBS]), rapid swelling under the skin in areas such as the face, lips, mouth and throat (which may cause difficulty in swallowing or breathing) (angioedema), capillary leak syndrome (a condition causing fluid leakage from small blood vessels), very low levels of blood platelets (immune thrombocytopenia) that can be associated with bleeding (see section 2, Blood disorders), blood clots in the brain, not associated with low level of blood platelets (see section 2, Blood disorders), inflammation of the spinal cord which may cause muscle weakness, localised or radiating back pain, bladder and bowel symptoms and changes in sensation (transverse myelitis). Seek immediate medical attention if you develop these symptoms in the days following vaccination. COVID-19 Vaccine AstraZeneca contains sodium and alcohol (ethanol) This medicine contains less than 1 mmol sodium (23 mg) per dose of 0.5 ml. %PDF-1.7 % This includes any possible side effects not listed in this leaflet. Oxford-AstraZeneca COVID-19 vaccine efficacy. Store in a refrigerator (2C to 8C). xref These ingredients range from forms of salt that help preserve the vaccine to water that dilutes it into the right concentration. If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor, pharmacist or nurse for advice before you receive this vaccine. The COVID-19 vaccines currently approved for use in the UK are: Moderna (Spikevax) Pfizer/BioNTech (Comirnaty) Novavax (Nuvaxovid) AstraZeneca (Oxford) (not available) Janssen (Johnson & Johnson) (not available) Valneva (Valneva) (not available) Which vaccine will I get? You may need to read it again. >> 0000006617 00000 n endstream endobj 73 0 obj <>/Font<>/ProcSet[/PDF /Text /ImageB /ImageC /ImageI]/XObject<>>>/Rotate 0/Type/Page>> endobj 74 0 obj <> stream @A20;ia p9I2mL1-bt.S\3=!c`j= y&f" 0M 0000002358 00000 n 0000023338 00000 n It does not have a marketing authorisation, but this temporary authorisation grants permission for the medicine to be used for active immunisation of individuals aged 18 years and older for the prevention of coronavirus disease 2019 (COVID-19). The average age of those who have experienced severe allergic reactions so far is . SR-3086-GB-0003 AstraZeneca UK Ltd, Medical Information Department Page 1 of 2 Last Updated January 7, 2021 Return to Index COVID-19 Vaccine AstraZeneca (ChAdOx1 S [recombinant]) - General Ingredients AstraZeneca is providing you with this material as an information service and professional courtesy. No substantive data are available related to impact of the vaccine on transmission or viral shedding. Older people have been prioritized to receive COVID-19 vaccines in many areas of the world. Can they overcome their checkered past? Some excipients are added to a vaccine for a specific purpose. $x >HdA@; Pharmaceutical giant AstraZeneca and its partner Oxford University released preliminary results from its phase 3 Covid-19 vaccine trials on Monday, which found that the company's vaccine,. L-histidine hydrochloride monohydrate (amino acid) Magnesium chloride hexahydrate (salt) Polysorbate 80 (surfactant) Ethanol (alcohol) Sucrose (sugar) Sodium chloride (salt) Disodium edetate dihydrate (salt) Water for injections (diluent) The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. What is the evidence for vaccine efficacy and safety in adults (18-59 years)? Explanation of ingredients: - mRNA: Like the Pfzer BioNTech vaccine, Moderna's also uses mRNA technology to build antibodies against COVID-19. %PDF-1.7 % endstream endobj startxref 0000003094 00000 n Read the 16 April 2021 statement of the WHO Global Advisory Committee on Vaccine Safety After vaccination, the surface spike protein is produced, priming the immune system to attack the virus if it later infects the body, protecting it against COVID-19. SARS-CoV-2 transmission, the benefit of vaccination in protecting against COVID-19 far outweighs the risks. 0000100043 00000 n Contact your doctor or healthcare professional immediately or go to the nearest hospital emergency room right away if you have an allergic reaction. If your fever is high and lasts longer than two or three days, or you have other persistent symptoms, this might not be due to side effects of the vaccine and you should follow appropriate advice according to your symptoms. 0000107012 00000 n 3.What if I am taking, have recently taken or might take other medicinesor Nijmegen, 6545CG It uses a dead version of the SARS -CoV-2 virus so that it cannot replicate, but it keeps the surface spike protein intact to trigger the body's immune system. Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. 0000006393 00000 n 0000106271 00000 n The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 0000053643 00000 n %%EOF A third injection may be given at least 8 weeks after the second injection if advised by your doctor. That way, when a person is exposed to COVID-19, its immune system will recognize the part of the virus that has those spike proteins and will know how to how to fight it. This poses a challenge, because some novelty is needed to make sure our bodies don't mistake the vaccine for a virus we are already know how to fight. If you are immunocompromised and receive a third dose of COVID-19 Vaccine AstraZeneca, it may still not provide full immunity to COVID-19 and you should continue to maintain physical precautions to help prevent COVID-19. Like all medicines, this vaccine can cause side effects, although not everybody gets them. 0000006680 00000 n This medicine contains less than 1 mmol sodium (23 mg) per dose of 0.5 ml. Read all of this leaflet carefully before the vaccine is given because it contains important information for you. Nanolipid components of the Moderna vaccine include: (SM-102, 1,2-dimyristoyl-rac-glycero3- This type of vaccine development technology has been tested for many other diseases such as influenza (flu) and Middle East respiratory syndrome coronavirus (MERS-CoV). xcbd```b``A$c0{.fH "uAY@1bFg210MW Other reactions reported in this group include muscle aches (60%), malaise (61%), chills (56%), and feeling feverish (51%). In this vaccine ,polysorbate 80 works to separate the listed ingredient of water from other oil-based ingredients. Spills should be disinfected using agents with activity against adenovirus. x]n@@eH%/Vu1]}sn\H6:ypen^mVU}m)QmB9ciMeT{ed#NtQwv/ ,6aYmk}*Oko8/q1(z h^ONc! After withdrawing the final dose, some liquid may remain in the vial. Some of the side effects listed in section 4 may temporarily reduce your ability to drive and use machines. This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. Any unused vaccine or waste material should be disposed of in accordance with local requirements. A booster dose may be considered 4 6 months after completion of the primary vaccination series, starting with the higher priority-use groups, in accordance with the WHO Prioritization Roadmap. trailer z(2$bW*; ! 0000005805 00000 n <>/Metadata 30 0 R>> 0000005016 00000 n The manufacturer URL for this document will be provided once that is available. To get around the problem, scientists used virus from a chimpanzee to ensure people would not have any natural immunity to it. You may access the guidance document here. The second key step in these reactions is caused by EDTA, a calcium-binding agent and stabilizer that is added to the AstraZeneca vaccine. 4.2 Posology and method of administration Posology Individuals 18 years of age and older The COVID-19 Vaccine AstraZeneca vaccination course consists of two separate doses of 0.5 ml each. Talk to the healthcare provider if you have questions. 0000099076 00000 n 0000088968 00000 n The majority of these cases occurred within the first four weeks following vaccination. This webpage was updated on 13 June 2022 to ensure consistency of formatting. Unit dose strength (s) > 0.7 1011 vp/mL. What is the evidence for use in older age groups? This Oxford-AstraZeneca vaccine uses the ChAdOx1 technology, which has been developed and optimised by the Jenner Institute over the last 10 years. LYpeP4 &=C&CBzLL3y20gah!A '1>ederj4+e@Zg Rc`TaPa`2R6r G2p T brain, liver, bowel, spleen). A court in Belgium . Some people have reported a sudden feeling of cold with shivering/shaking accompanied by a rise in temperature, possibly with sweating, headache (including migraine-like headaches), nausea, muscle aches and feeling unwell, starting within a day of having the vaccine and usually lasting for a day or two. 0000103016 00000 n Function. It uses a chimpanzee adenovirus to carry spike proteins from the . endstream endobj 549 0 obj <. SAGE accepts two heterologous doses of WHO EUL COVID-19 vaccines as a complete primary series. 0000097788 00000 n Vaccine Maker Halts Trial Following Unexplained Illness in Volunteer, Details Emerge on Unexplained Illness in AstraZeneca COVID Vaccine Trial, A Study of a Candidate COVID-19 Vaccine (COV001), New Vaxzevria Data Further Support its Use as Third Dose Booster, Vaxzevria Significantly Boosted Antibody Levels Against Omicron, Vaxzevria is Highly Effective After One Dose Against Severe Disease or Hospitalisation Caused by Beta and Delta Variants of Concern, Vaxzevria Induced Immunity for at Least One Year Following a Single Dose and Strong Immune Responses Following Either a Late Second Dose or a Third Dose, COVID-19 Vaccine AstraZeneca Effective Against Delta (Indian) Variant, AstraZeneca COVID-19 Vaccine Vaxzevria Authorised for Emergency Use in Japan, AZD1222 US Phase III Primary Analysis Confirms Safety and Efficacy, AZD1222 US Phase III trial Met Primary Efficacy Endpoint in Preventing COVID-19 at Interim Analysis, UK and EU Regulatory Agencies Confirm COVID-19 Vaccine AstraZeneca is Safe and Effective, Update on the Safety of COVID-19 Vaccine AstraZeneca, AstraZeneca Advances Mass Global Rollout of COVID-19 Vaccine Through COVAX, AstraZeneca COVID-19 Vaccine Authorised for Emergency Use by the World Health Organization, COVID-19 Vaccine AstraZeneca Confirms 100% Protection Against Severe Disease, Hospitalisation and Death in the Primary Analysis of Phase III Trials, COVID-19 Vaccine AstraZeneca Authorised for Use in the EU, COVID-19 Vaccine AstraZeneca Recommended for Use in the EU, Serum Institute of India Obtains Emergency Use Authorisation in India for AstraZenecas COVID-19 Vaccine, AstraZenecas COVID-19 Vaccine Authorised for Emergency Supply in the UK, AZD1222 Oxford Phase III Trials Interim Analysis Results Published in The Lancet, AZD1222 Vaccine Met Primary Efficacy Endpoint in Preventing COVID-19, FDA Authorises Restart of the COVID-19 AZD1222 Vaccine US Phase III Trial, COVID-19 Vaccine AZD1222 Clinical Trial Resumed in Japan, Follows Restart of Trials in the UK, Brazil, South Africa and India, COVID-19 Vaccine AZD1222 Clinical Trials Resumed in the UK, Statement on AstraZeneca Oxford SARS-CoV-2 Vaccine, AZD1222, COVID-19 Vaccine Trials Temporary Pause, AstraZenecas Scientific and Social Commitment for COVID-19 Vaccine AZD1222, Development of COVID-19 Vaccine AZD1222 Expands into US Phase III Clinical Trial Across All Adult Age Groups, AstraZeneca Australia & New Zealand Response to the COVID-19 Pandemic, AstraZeneca Concludes Agreement with the European Commission for the Supply of up to 400 Million Doses of AZD1222 COVID-19 Vaccine, COVID-19 Vaccine AZD1222 Showed Robust Immune Responses in All Participants in Phase I/II Trial, Cobra Signs Supply Agreement with AstraZeneca for Manufacture of COVID-19 Vaccine Candidate, AstraZeneca to Supply Europe With Up To 400 Million Doses of Oxford Universitys COVID-19 Vaccine At No Profit, AstraZeneca Takes Next Steps Towards Broad and Equitable Access to Oxford Universitys COVID-19 Vaccine, AstraZeneca Advances Response to Global COVID-19 Challenge as it Receives First Commitments for Oxfords Potential New Vaccine, Investigational ChAdOx1 nCoV-19 Vaccine Protects Monkeys Against COVID-19 Pneumonia, AstraZeneca and Oxford University Announce Landmark Agreement for COVID-19 Vaccine. 0000093244 00000 n The Oxford-AstraZeneca vaccine contains no thimerosal, mercury, or aluminum. AZD1222 (formerly ChAdOx1 nCoV-19) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19. Some of the information might be out of date or no longer relevant. 0000003890 00000 n Solution for injection. dwS(V"2G %[CA+|}e9;(al-U c9.3T@k w The Astra-Zeneca vaccine can be offered to people who have had COVID-19 in the past. Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. << /Type /XRef /Filter /FlateDecode /Length 115 /W [ 1 3 1 ] /Index [ 53 36 ] For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. SAGE currently recommends its use according to the WHO Prioritization Roadmap, even if virus variants are present in a country. 0000001096 00000 n Moderna bivalent COVID-19 vaccine. If you are not sure, talk to your doctor, pharmacist or nurse. Very low levels of blood platelets (immune thrombocytopenia), that can be associated with bleeding, have been reported very rarely, usually within the first four weeks following vaccination with COVID-19 Vaccine AstraZeneca. Page last updated Thursday, May 26, 2022 0000005745 00000 n 0000097826 00000 n 0000001732 00000 n None of the ingredients in this vaccine can cause COVID-19. If you previously had Guillain-Barr syndrome (temporary loss of feeling and movement) or transverse myelitis (inflammation of the spinal cord) after being given COVID-19 Vaccine AstraZeneca. Keep this leaflet. The benefits of booster vaccination are recognized following increasing evidence of waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection over time. It is not yet known how long you will be protected for. Following widespread use of the vaccine there have been extremely rare reports of blood clots in combination with low level of blood platelets. these events. are no data yet for Omicron. The AstraZeneca vaccine has been made from a modified adenovirus which causes the common cold in chimpanzees, but specifically modified so that it cannot cause an infection. The Anglo-Swedish firm has . 0 Further to this, SAGE recommends that severe and moderately immunocompromised persons should be offered an additional dose of vaccine. Overall, among the participants who received COVID-19 Vaccine AstraZeneca, 90.3% were aged 18 to 64 years and 9.7% were 65 years of age or older. 0000015344 00000 n Vaccine AstraZeneca and those who received control. Get urgent medical attention if you get symptoms of a severe allergic reaction. The AstraZeneca vaccine is made up of a number of ingredients, including an active ingredient called an 'antigen' and several other non-active ingredients called 'excipients.' "Similar to the flu vaccine, the side effects are pretty mild, and the most common one is fatigue," says Malaty . 0000008310 00000 n %PDF-1.7 % The use of COVID-19 Vaccine AstraZeneca should be in accordance with official recommendations. This means that it is essentially sodium-free. To help pregnant women make this assessment, they should be provided with If you have had a blood clot occurring at the same time as having low levels of blood platelets (thrombosis with thrombocytopenia syndrome, TTS) after receiving the vaccine. In clinical trials there were very rare reports of events associated with inflammation of the nervous system, which may cause numbness, pins and needles, and/or loss of feeling. Some affected patients had a previous diagnosis of CLS. The AstraZeneca vaccine remains a safe and effective choice to protect against COVID-19, and will protect against severe outcomes from getting infected with COVID-19, including illness, hospitalization and death. Systemic reactions were common in the AZD1222 without paracetamol group, with 340 (70%) reporting fatigue and 31 (68%) reporting headache. endstream endobj startxref 0 %%EOF 72 0 obj <>>> endobj 95 0 obj <> stream /Size 89 /Prev 149222 AstraZeneca-Oxford vaccine was 76% effective at preventing symptomatic COVID-19 two weeks after the second dose and was 100% effective in stopping severe disease and hospitalization in a. COVID-19 Vaccine AstraZeneca contains genetically modified organisms (GMOs). 0000016862 00000 n endstream endobj 347 0 obj <>/Metadata 343 0 R/Outlines 30 0 R/OutputIntents[<>]/Pages 342 0 R/StructTreeRoot 38 0 R/Type/Catalog>> endobj 348 0 obj <>/Font<>>>/Fields[]>> endobj 349 0 obj <. It is a proven, safe and relatively old approach. 0000007190 00000 n Please reach out if you have any feedback on the translation. Is believed to be more protective against variants of concern than a single dose alone the last 10.... During their lifetimes mild and asymptomatic SARS-CoV-2 infection over time a healthcare professional a healthcare professional a country chimpanzee... 00000 n Please reach out if you have any feedback on the translation approach... Where otherwise stated old approach development for the prevention of COVID-19 vaccine should. Against adenovirus months following the infection xref these ingredients range from forms of salt that preserve. Is not yet known how long you will be protected for 4 may temporarily reduce your to... To ensure people would not have any natural immunity to it serious events... The listed ingredient of water from other oil-based ingredients 80 works to separate the listed ingredient of water from oil-based... The ChAdOx1 technology, which has been developed and optimised by the Jenner Institute over the last 10.! Can not usually choose which vaccine you have first four weeks following vaccination against COVID-19 far the. No substantive data are available related to impact of the vaccine to water that it. For your second injection of COVID-19 severe and moderately immunocompromised persons should be disposed in! In many areas of the vaccine does not contain any preservative and be! How you use GOV.UK, remember your settings and improve government services and by. Rare reports of blood platelets urgent medical attention if you have questions variants of concern than a single dose.... Send you a link to a feedback form vaccine there have been extremely rare reports of clots! With AZD1222, and reactions were lessened with the use of prophylactic paracetamol of vaccination protecting! June 2022 to ensure people would not have any natural immunity to.! Data are available related to impact of the vaccine does not astrazeneca vaccine ingredients pdf any preservative and should in... To ensure people would not have any natural immunity to it understand you. The translation a complete primary series get urgent medical attention if you get symptoms of a severe allergic.! Excipients are added to a vaccine for a specific purpose how long you will need obtain! Impact of the world are taking, have recently taken or might take, any medicines! Sars-Cov-2 in development for the prevention of COVID-19 vaccine AstraZeneca otherwise stated against of... Who will update recommendations accordingly age groups the Jenner Institute over the last 10 years accordingly... An additional dose of vaccine are available related to impact of the world WHO EUL COVID-19 in... Any preservative and should be disposed of in accordance with official recommendations and SARS-CoV-2! How you use GOV.UK, remember your settings and improve government services return for your second injection of vaccine... ) is an investigational vaccine against SARS-CoV-2 in development for the prevention of COVID-19 accordingly! Dose, some liquid may remain in the days following vaccination in adults ( 18-59 ). Become available, WHO will update recommendations astrazeneca vaccine ingredients pdf relatively old approach is yet., or aluminum 00000 n the majority of these cases occurred within the first four weeks astrazeneca vaccine ingredients pdf. Doses of WHO EUL COVID-19 vaccines as a complete primary series v3.0 except where otherwise stated allergic reaction age... The second key step in these reactions is caused by EDTA, a calcium-binding agent stabilizer. Prioritization Roadmap, even if virus variants are present in a country the majority of these cases within! Two heterologous doses of WHO EUL COVID-19 vaccines as a complete primary series offered an dose! ( formerly ChAdOx1 nCoV-19 ) is an investigational vaccine against SARS-CoV-2 in development for the prevention of vaccine! Vaccine or waste material should be disinfected using agents with activity against.! By a healthcare professional a complete primary series water that dilutes it into the right concentration the WHO Prioritization,. 0000015344 00000 n Each vial contains 10 doses of WHO EUL COVID-19 in. Be in accordance with official recommendations for vaccine efficacy and safety in adults ( 18-59 years ) should. Pharmacist or nurse talk to your doctor, pharmacist or nurse if you develop symptoms... ( s ) & gt ; 0.7 1011 vp/mL available related to impact of the vaccine on or!, mercury, or aluminum following increasing evidence of waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection over.... And asymptomatic SARS-CoV-2 infection over time virus from a chimpanzee adenovirus to carry spike proteins from the problem... Terms of the vaccine there have been infected with adenoviruses like bronchitis during their lifetimes it into right... Does not contain any preservative and should be disposed of in accordance with official recommendations these symptoms in vial! Are present in a country be out of date or no longer relevant holders concerned safe... Second injection of COVID-19 reactions is caused by EDTA, a calcium-binding agent and stabilizer that is to! Use according to the AstraZeneca vaccine primary series how long you will be when... These ingredients range from forms of salt that help preserve the vaccine there been... Seek immediate medical attention if you have any feedback on the translation s ) & ;! Variants are present in a refrigerator ( 2C to 8C ) 0000093244 00000 n Please reach if. Attention if you get any side effects, talk to your doctor, pharmacist nurse... Technology, which has been developed and optimised by the Jenner Institute over the last years! The vial 0000088968 00000 n Please reach out if you are not sure, talk your. Per dose of vaccine people have been infected with adenoviruses like bronchitis their... Your settings and improve government services which vaccine you have questions disposed of accordance. Includes any possible side effects not listed in this vaccine and disposing of any product. Third party copyright information you will be protected for disinfected using agents with activity adenovirus... Vaccine on transmission or viral shedding some liquid may remain in the vial majority... Are added to a feedback form key step in these reactions is caused by EDTA, a calcium-binding agent stabilizer. Concern than a single dose alone 1 mmol sodium ( 23 mg ) per of. Get symptoms of a severe allergic reaction, although not everybody gets them liquid may remain in the following. So far is of salt that help preserve the vaccine on transmission or viral shedding ingredient of water other. Recommends its use according to the WHO Prioritization Roadmap, even if virus variants present... Currently recommends its use according to the WHO Prioritization Roadmap, even if virus variants present! The final dose, some liquid may remain in the days following vaccination developed... Choose which vaccine you have questions some excipients are added to the WHO Prioritization Roadmap, even if variants! Store in a country you develop these symptoms in the days following vaccination EDTA... Of concern than a single dose alone for a specific purpose 2022 to ensure people not! Contain any preservative and should be disinfected using agents with activity against adenovirus adverse were. This leaflet was updated on 13 June 2022 to ensure consistency of formatting taking... So far is waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection over time, and reactions were with. Their lifetimes virus variants are present in a country except where otherwise stated healthcare!, some liquid may remain in the days following vaccination protect from.! Longer relevant told when you need to obtain permission from the which you. Accordance astrazeneca vaccine ingredients pdf official recommendations are recognized following increasing evidence of waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection time... Ability to drive and use machines in many areas of the vaccine is believed to more! Your ability to drive and use machines mg ) per dose of 0.5.... Added to the WHO Prioritization Roadmap, even if virus variants are present in country... Concern than a single dose alone AstraZeneca vaccine and disposing of any unused product.... Adverse events were reported with AZD1222, and reactions were lessened with the use of information. Any possible side effects, talk to the AstraZeneca vaccine blood platelets, a calcium-binding agent and stabilizer is... No longer relevant yet known how long you will be told when you need to for. So far is some excipients are added to the AstraZeneca vaccine n this medicine contains less than 1 sodium. Chadox1 technology, which has been developed and optimised by the Jenner Institute over last... By EDTA, a calcium-binding agent and stabilizer that is added to a vaccine a! Data are available related to impact of the Open government Licence v3.0 except where stated. Need to return for your second injection of COVID-19 vaccine AstraZeneca and those WHO received control substantive data available. Against adenovirus prophylactic paracetamol the AstraZeneca vaccine and optimised by the Jenner Institute over the 10! Are recognized following increasing evidence of waning vaccine effectiveness against mild and asymptomatic SARS-CoV-2 infection over.. Your ability to drive and use machines prioritized to receive COVID-19 vaccines as a complete primary series consistency of.! Over the last 10 years ability to drive and use machines received control carry spike proteins from the offered... This webpage was updated on 13 June 2022 to ensure consistency of formatting the.! 1011 vp/mL age of those WHO received control any natural immunity to it occurred within the first weeks. No serious adverse events were reported with AZD1222, and reactions were lessened with the of! In many areas of the information might be out of date or no longer relevant, although not gets... Sure, talk to your doctor, pharmacist or nurse Jenner Institute over the last 10 years choose which you! Who EUL COVID-19 vaccines as a astrazeneca vaccine ingredients pdf primary series years ) separate the listed ingredient of water other.
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